Pivot Point Skin 106 Practice Test

When skin temperature rises, absorption increases because diffusion through the skin becomes more efficient. Warmer skin boosts molecular motion, raises the diffusion coefficient, and makes the lipid-rich barrier of the stratum corneum more fluid, all of which help molecules penetrate more readily. That direct link to heat explains why this factor is the best choice when considering how temperature affects skin uptake.

Hydration and occlusion can influence absorption by changing water content and sometimes temperature, but they don’t directly describe the role of skin temperature itself. The size of the molecule matters for how easily it passes through, but it doesn’t address the temperature-dependent change in permeability.